This Single Molecule Drives Cancer Cells to Suicide

Jamie Condliffe
FEB 8, 2013 8:56 AM

A team of researchers has identified a single molecule, called TIC10, that kick-starts the body’s tumor-destroying systems—causing a chain reaction that can kill cancer dead.

In a series of experiments in mice the researchers, from Pennsylvania State University, found that TIC10 activities the gene for a protein called TRAIL—that’s short for tumour-necrosis-factor-related apoptosis-inducing ligand—which causes cancerous cells to commit suicide. Wafik El-Deiry, one of the researchers explains:

“TRAIL is a part of our immune system: all of us with functional immune systems use this molecule to keep tumours from forming or spreading, so boosting this will not be as toxic as chemotherapy.”

Read more: This Single Molecule Drives Cancer Cells to Suicide — GIZMODO.

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