How to assemble designer biomolecular nanomachines
October 1, 2012

Assembling novel biomolecular machines requires nanometer precision. Ludwig Maximilian University (LMU) researchers have now found a way to acheive it.

The finely honed tip of the atomic force microscope (AFM) allows one to pick up single biomolecules and deposit them elsewhere with nanometer accuracy. The technique is referred to as Single-Molecule Cut & Paste (SMC&P), and was developed by the research group led by LMU physicist Professor Hermann Gaub.

It was initially only applicable to DNA molecules, but the molecular machines responsible for many of the biochemical processes in cells consist of proteins.

So a practical method of manipulating proteins is required. It would provide novel insights into the workings of living cells and would furnish a way to develop, construct, and utilize designer nanomachines.

Read more: How to assemble designer biomolecular nanomachines | KurzweilAI.

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