Inhibiting certain miRNA molecules can improve heart
cell regeneration in adult mammals following injury.
Credit: iStockphoto

Clues to mystery of heart regeneration failure in humans

Thursday, 10 January 2013
by Biplab Das

COSMOS Online

KOLKATA: Why does adult human heart fail to regenerate following a heart attack? A new study may have found the answer to this long-standing puzzle by simulating human-like heart attacks in newborn and adult mice.

A team of researchers led by Eric Olson from University of Texas Southwestern Medical Center, Dallas and University of Queensland (UQ), Australia, has solved the puzzle of adult mammalian heart’s regeneration failure, which they claim could open up new avenues to replenish heart cells lost in a heart attack.

“This may usher in a new era of… therapy to repair damaged heart caused by heart attack,” said Enzo Porrello, from UQ and lead author of the study published in the journal Proceedings of the National Academy of Sciences.

Read more: Clues to mystery of heart regeneration failure in humans | COSMOS magazine.

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